As I learn to use my histogram, I am trying out a lazy version of "expose to the right", not wanting to mess with exposure compensation in post-processing unless this is needed to hold important shadow detail. I could call it keep away from the left.
In this laziness, the only time I feel a need to increase exposure is when I have both significant stuff near the left end of the histogram AND spare room at the right of the histogram; an "empty" part at the right.
How close one can safely go to the left is something to work out for the histogram of a particular camera (and maybe for different settings on the same camera, like RAW vs JPEG output). Maybe a useful threshold is the point on the histogram corresponding to about two or three stops below the mid-tones, or wherever your shadows start to crumble.
Calibrated like that, it does not matter if the scale is linear, logarithmic, or whatever.
That is, if the histogram is almost emply at the left, then it does not matter if the right end of the histogram is also empty, it just means that you have an easy, moderate contrast subject and so plenty of exposure latitude. Sometimes, this latitude might be best used to increase sharpness, through increased DOF or increased shutter speed at the lowest safe exposure level for the subject. (Similar to what Ansel Adams suggests with low contrast subjects, despite the very different technology!)

