While waiting (oh so patiently) for a good friend to get his old Epson 2200 out of storage and kindly donate it to my cause .... I got paid on a job I thought was a freebie ... so I bought an Epson r2880.

Here's my dumb, yet very hopeful question ....

Can one use Eric Chan's terrific 3800 profiles with the 2880?

No - 2880 uses Vivid Magenta instead of Magenta, probably different screening algorithms and linearisation.